Bone Marrow Stimulating Techniques: Autologous Matrix-Induced Chondrogenesis (AMIC)

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Chapter 4C Bone Marrow Stimulating Techniques

Autologous Matrix-Induced Chondrogenesis (AMIC)

Surgical Principles and Objective

Postoperative Treatment

Thrombosis prophylaxis should be used from the start of the operation. Medication, ice application, lymph drainage, and muscle stimulation or electrotherapy can be part of the postoperative treatment.

References

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2. Behrens P, Benthien JP. Autologous matrix-induced chondrogenesis (AMIC): a one-step procedure for retropatellar resurfacing. Acta Orthop Belgica 2010 Apr; 76(2):260-3.

3. Behrens P, Benthien JP. Autologous matrix-induced chondrogenesis (AMIC): combining microfracturing and a collagen I/III matrix for articular cartilage resurfacing. Cartilage 2010; I(1)65-68.

4. Behrens P., Bosch U., Bruns J., Erggelet C., Esenwein S.A., Gaissmaier C., Krackhardt T., Löhnert J., Marlovits S., Meenen N.M., Mollenhauer J., Nehrer S., Niethard F.U., Nöth U., Perka C., Richter W., Schäfer D., Schneider U., Steinwaschs M., Weise K. German Society for Traumatology; German Society for Orthopedic Surgery. Indications and implementation of recommendations of the working group “Tissue Regeneration and Tissue Substitutes” for autologous chondrocyte transplantation (ACT). Z Orthop Ihre Grenzgeb. 2004 Sep-Oct;142(5):529-539. Review. German

5. Behrens P., Bitter T., Kurz B., Russlies M. Matrix-associated autologous chondrocyte transplantation/implantation (MACT/MACI)–5-year follow-up. Knee. 2006 Jun;13(3):194-202. Epub 2006 Apr 24

6. Anders S., Schaumburger J., Schubert T., Grifka J., Behrens P. Matrix-associated autologous chondrocyte transplantation (MACT). Minimally invasive technique in the knee. Oper Orthop Traumatol. 2008 Sep;20(3):208-219. German

7. Skodacek D., Brandau S., Deutschle T., Lang S., Rotter N. Growth factors and scaffold composition influence properties of tissue engineered human septal cartilage implants in a murine model. Int J Immunopathol Pharmacol. 2008 Oct-Dec;21(4):807-816.

8. Gille J., Schuseil E., Wimmer J., Gellissen J., Schulz A.P., Behrens P. Mid-term results of autologous matrix-induced chondrogenesis for treatment of focal cartilage defects in the Knee. Knee Surg Sports Traumatol Arthrosc. 2010 Feb 2. Epub