Basic Pharmacokinetics

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CHAPTER 28 Basic Pharmacokinetics

Pharmacokinetics is the study of the rate of movement of drugs within biological systems, or the study of what the body does to the drug, as characterized by drug absorption, distribution, metabolism, and excretion (ADME). It establishes a time course of the drug in the body and helps optimize drug therapy (Figure 28-1).

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Figure 28-1 Concentration and time of drug action.

(Reprinted by permission from Macmillan Publishers Ltd: International Journal of Impotence Research, 19:253-264, Sept. 21, 2006.)