Chapter 29
Assessment of Nutritional Status1
One must eat to live, and not live to eat.
Jean Baptiste Molière (1622–1673)
Nutrition is one of the most important factors involved in an individual’s health and disease because it affects almost every system. It has been shown that dietary habits contribute importantly to the pathogenesis of many of the major causes of death in the United States.
One of the most challenging nutritional problems in the world today is obesity. In 2008, more than 1.4 billion adults, 20 and older, were overweight. Of these, more than 200 million men and nearly 300 million women were obese. In the United States, the prevalence of obesity doubled among adults between 1980 and 2004, affecting more than 68% of adults and 33% of children and adolescents. Minority populations are particularly at risk, with 76% of African-American adults and 80% of Mexican-American adults either overweight or obese. Obesity is a risk factor for many diseases, including hypertension, coronary artery disease, diabetes, obstructive sleep apnea, osteoarthritis, cancers of the breast and endometrium, and hepatobiliary disease. There is an increased awareness of obesity, but it remains a major problem. The overall cost to society of obesity is estimated to be more than $100 billion per year.
Malnutrition is also a problem in the United States. Surveys have shown that among general medical and surgical admissions to hospitals, approximately 50% of the patients suffer from some form of malnutrition. Approximately 25% may actually have functional disease related to it, and 10% may have evidence of advanced malnutrition. Malnutrition is a problem that targets a number of specific populations, including older persons who live alone, chronically ill patients, adolescents who eat and diet erratically, and patients with recently diagnosed cancer in whom chemotherapeutic and radiation therapeutic protocols may promote nutritional problems. Even obese patients may suffer from malnutrition, most commonly secondary to catabolic stress.
Health care providers have a unique opportunity to educate patients and help modify their behavior. More than half of these health-promoting behaviors are nutrition related. They include balancing caloric intake to match energy expenditure, limiting salt consumption, reducing cholesterol intake, taking vitamins, and decreasing dietary saturated fat consumption. The health care professional must have a firm understanding of clinical nutrition and its influence on health and illness. A patient’s ability to recover from an illness or from surgery depends, in many cases, on his or her past and current nutritional status. Adequate protein-calorie nutrition is important for wound healing, recovery from infection, and responsiveness to treatment, and protein-calorie malnutrition may be a factor in development of decubitus ulcers and wound disruption. Five of the leading causes of death in this country—heart disease, cancer, stroke, diabetes mellitus, and atherosclerosis—are diet-related. Therefore, knowing what patients eat, the nutritional adequacy of their diets, and their clinical nutritional status is a necessary component of physical diagnosis.
This chapter focuses on the aspects of the history and physical examination that constitute a nutritional assessment. At present, there is no standardized set of dietary history questions or method for assessing nutritional status. Rather, nutritional assessment requires the integration of information obtained from the medical history and physical examination. Throughout this chapter, nutritionally focused questions and examples of diet-related diseases are provided to assist in building history-taking and physical examination skills. The chapter begins with a review of the medical history and physical examination, demonstrating the integration of nutritionally focused information. Then it covers the nutritional assessment of select patient groups, followed by some pathophysiologic correlations.
Medical History
Chief Complaint
Often the chief complaint is directly related to the patient’s nutrition, which may affect treatment and prognosis. The most commonly voiced nutritional concerns are “loss of appetite,” “weight loss,” “weight gain,” and “weakness.” Changes in dietary intake and in weight are among the earliest signs of medical problems. These complaints should prompt a detailed inquiry about diet and related symptoms in the history of present illness.
History of Present Illness
After asking the patient to describe the symptoms or medical problem that caused him or her to seek medical attention, begin to explore any diet-disease relationship that may exist. The following self-directed questions should guide your inquiry:
Body Weight History
Body weight is a global indicator for overall health. Any weight loss is a good general indication of the severity or systemic nature of the presenting symptoms, whether they are acute or chronic. Both low body weight and unintentional weight loss have been shown to be predictive of increased morbidity and mortality. Although the cause of weight loss is often linked to the presenting medical problem, often no identifiable physical cause is apparent. In all cases, the underlying reasons for the weight change should be explored and the amount of weight loss clearly defined. Information-yielding questions include the following:
“How much weight did you lose or gain?”
“What was your weight before the symptoms started?”
“During what period did you experience the weight loss or gain?”
“How was your appetite over this time?”
“Do you know what may have contributed to your change in weight?”
Rapid weight gain is often an indicator of fluid retention and may be accompanied by edema or ascites. Common diseases associated with rapid weight gain include congestive heart failure, liver disease, and renal disease. In contrast, rapid weight loss usually signifies loss of body tissue, unless the patient has been undergoing therapeutic diuresis (in which case the patient would report markedly increased urination) or is experiencing dehydration (in which case the patient would report decreased fluid ingestion, dry mouth, weakness, and dizziness). If the patient has experienced weight loss, it is useful to think in terms of the percentage of weight lost over a specific time frame. To convert absolute pounds into percentage lost, the following simple equation is used:
Significant involuntary weight loss is generally defined as more than 5% of usual weight during the preceding 6 months or 10% or more within the year. When a patient has experienced weight loss, it is useful to direct your questions toward the underlying causes. There are four physiologic categories for weight loss: (1) decreased caloric intake, (2) malabsorption or maldigestion, (3) impaired metabolism or increased requirements, and (4) increased losses or excretion (Table 29-1).
Past Medical History
As patients list their past illnesses, the health care provider should consider the role of nutrition or diet in the cause or treatment. Common diet-related diseases include cardiovascular disease (coronary artery disease, peripheral vascular disease, cerebrovascular disease), hypertension, diabetes, hyperlipidemia, some forms of cancer, nonalcoholic fatty liver disease, and other gastrointestinal (GI) diseases. In addition to asking how the illness was diagnosed and what treatment was rendered, ask the patient whether he or she received dietary counseling or altered his or her diet in response to the diagnosis. Try to ascertain the patient’s understanding of the role that diet plays in the condition.
Past Surgical History
All surgical procedures should be recorded in this section, along with serious surgical complications such as draining fistulas, abscesses, open wounds, and chronic blood loss. These complications often lead to malnutrition and the need for specialized nutritional support, including enteral and parenteral feedings. If the patient is currently in the postoperative period, you should consider the role of nutritional support in the recovery process and how the particular surgery has altered the patient’s dietary habits and requirements. For example, a patient with a total gastrectomy needs to alter his or her diet to reduce simple sugars, eat multiple small meals each day, and receive supplemental vitamin B12 and iron to maintain good nutritional health.
Medications
The medication history should include both prescription and over-the-counter medications. Because complementary and alternative therapies have become popular, many patients take vitamins, minerals, herbs (Table 29-2), and other dietary supplements that they may not mention without prompting. A thorough review of alternative therapy use should be a standard part of the patient medication and lifestyle history. When eliciting this information, be careful not to be judgmental or accusatory. Many patients do not disclose this information because of fear of being censured. Suggested questions are as follows:
“What is the reason you are taking the supplement?”
“Have you experienced any side effects or benefits from the supplements?”
“Is anybody monitoring you, such as your doctor, nutritionist, or herbalist?”
“What is your consumption of grapefruit and grapefruit juice?”
Table 29–2
Commonly Used Herbs and Their Side Effects
Herb | Common Use | Side Effect and Interaction |
Echinacea | Treatment and prevention of upper respiratory infections, common cold | Rash, pruritus, dizziness |
St. John’s wort | Treatment of mild to moderate depression | Gastrointestinal upset, photosensitivity |
Gingko biloba | Treatment of dementia | Mild gastrointestinal distress, headache; may have anticoagulant effects |
Garlic | Treatment of hypertension, hypercholesterolemia, atherosclerosis | Gastrointestinal upset, gas, reflux, nausea, allergic reaction, antiplatelet effects |
Saw palmetto | Treatment of benign prostatic hyperplasia | Uncommon |
Ginseng | General health promotion, energy | High doses: diarrhea, hypertension, insomnia, nervousness |
Goldenseal | Treatment of upper respiratory infections, common cold | Diarrhea, hypertension, vasoconstriction |
Aloe | Topical application for dermatitis, herpes | Possible delay in wound healing after topical application; diarrhea and hypokalemia with oral use |
Siberian ginseng | Similar to those of ginseng | May alter digoxin levels |
Valerian | Treatment of insomnia, anxiety | Fatigue, tremor, headache, paradoxical insomnia |
Drugs and nutrients interact in many ways to affect both nutritional status and the effectiveness of drug therapy. Drugs may influence nutritional status by several physiologic mechanisms: altering food intake (through changes in appetite, nausea, altered taste sensations), producing malabsorption (through alterations in intestinal mucus, motility, or pH; competition with nutrients for absorption sites; binding of bile acids), or modifying excretion (through renal tubular reabsorption or secretion). Drug-induced nutrient deficiencies usually develop slowly and are more likely in patients who use drugs chronically, especially older adults. Other risk factors include high drug dosages, multiple drug dosages, multiple drug regimens, poor diets, and marginal nutrient stores. Table 29-3 lists examples of drug interactions and nutrient metabolism.
Table 29–3
Drug Interactions and Nutrient Metabolism
Drug Class and Examples | Nutrients Affected |
Antacids | |
Aluminum hydroxide | Phosphorus |
Magnesium trisilicate | Iron |
Antibiotics | |
Tetracyclines | Calcium, magnesium, iron, vitamin B12 |
Neomycin, kanamycin | Fat-soluble vitamins, vitamin B12 |
Sulfasalazine | Folate |
Anticonvulsants | |
Phenobarbital, phenytoin | Calcium, vitamin D, folate |
Hypolipidemics | |
Cholestyramine, colestipol | Fat and fat-soluble vitamins |
Cytotoxic agents | |
Methotrexate | Folate |
Laxatives | |
Mineral oil | Water, electrolytes, fat, and fat-soluble vitamins |
Antituberculotics | |
Isoniazid | Pyridoxine (vitamin B6) |
Anticoagulants | |
Warfarin | Vitamin K |
Analgesics | |
Aspirin, nonsteroidal anti-inflammatory drugs | Iron |
Diuretics | |
Thiazides, furosemide | Potassium, magnesium, calcium, zinc |
Antineoplastic agents | |
Cisplatin | Potassium, magnesium |
Studies by Bailey and associates (1998) revealed possible drug interactions involving grapefruit and grapefruit juice (fresh or frozen) with several common medications used to treat high blood pressure, anxiety, depression, cancer, gastroesophageal reflux disease, erectile dysfunction, angina, convulsions, and human immunodeficiency virus infection and acquired immune deficiency syndrome. In general, the grapefruit or its juice tends to increase the drug’s effect. The advisory also cautioned that sour oranges and tangelos may also interfere with medication blood levels. Other citrus fruits were considered safe. The study stated that as little as one 8-oz (0.26-mg) glass of grapefruit juice could increase the blood drug level and the effects could last for 3 days or more.
Allergies and Food Intolerances
In addition to asking about allergies to medications and environmental allergens, the interviewer should inquire about allergies and intolerances to food. The most common allergenic foods among adults are peanuts, tree nuts, shellfish, fish, eggs, soy, wheat, and milk. The first four foods listed may cause life-threatening reactions. If the patient states that he or she has a food allergy, the interviewer should ask what happens when those foods are eaten. Allergic symptoms may affect the respiratory tract (rhinorrhea, sneezing, wheezing, chest tightness, laryngeal edema), skin (urticaria, angioedema, pruritus, erythematous macular rash), or GI tract (nausea, vomiting, diarrhea, abdominal cramping).
A food allergy needs to be differentiated from food intolerance. Symptoms of food intolerance are usually confined to the GI tract and may be acute or chronic. Upper GI tract symptoms of belching and bloating may be due to aerophagia (swallowing air during the ingestion of food or drink), which is commonly associated with smoking, eating rapidly or talking while eating, chewing gum and hard candy, or ingesting carbonated beverages. Chronic lower GI tract symptoms of bloating, cramping, flatulence, or diarrhea may result from the ingestion of sugar substitutes (sorbitol, xylitol) or fructose, high fiber intake, or lactase deficiency. Of these potential causes, lactose intolerance is the most common, affecting 25% of the population in the United States and up to 80% of African Americans. In lactose-intolerant individuals, symptoms occur after the consumption of products containing lactose, including milk, cheese, ice cream, yogurt, and some processed foods.
Social History
Multiple social factors affect the dietary and nutritional status of patients. For example, low socioeconomic status, low fixed income, homelessness, food insecurity (the uncertainty of having or being able to acquire enough food because of insufficient funds or other resources) or lack of access to a variety of food choices may contribute to nutritional deficiencies. Chronic alcoholism and recreational drug use are two additional conditions that put people at high nutritional risk. The patient’s attitudes about food and nutrition, as well as religious observances, also determine eating patterns and the selection or avoidance of specific foods. This information is important to note and document.
Lifestyle Habits
The lifestyle habits section of the medical history includes the dietary history, physical activity history, alcohol use history, and smoking history. Questions related to alcohol use and smoking are discussed in Chapter 1, The Interviewer’s Questions.
Dietary History
The dietary history provides information about the patient’s food habits, diet, and any counseling he or she may have received. Depending on the patient’s medical problems, the dietary history may be brief or comprehensive. It is often difficult to obtain accurate information about a patient’s diet because of variability, general lack of focus on what is eaten, and forgetfulness. For this reason, the primary goal is to obtain a qualitative description of eating patterns and the foods and beverages that are habitually chosen, along with any dietary changes that occurred over the course of the illness. Three methods are commonly used: a 24-hour intake recall, a typical day, and food frequency.
A 24-hour intake recall is used extensively and may be broached as follows: “Please tell me what you had to eat and drink for the entire day yesterday. Could you start with the first item you had to eat or drink and bring me through the entire day? I would also like to know the times you ate and the amounts.” The advantage of this method is that patients can usually remember what they ate over the course of one recent day. The disadvantage is that one particular day may not adequately depict the patient’s usual diet, especially if there has been a recent change.
The preferred method is to ask the patient to describe a typical day. A good opening is, “I would like to know about your usual or typical diet. Can you bring me through a typical day, starting with the first item you eat or drink? I would also like to know the times you eat and the amounts.” The advantage is that you are more likely to capture a picture of the patient’s habitual diet. If the patient states that every day is different and there are no typical days, then ask him or her to describe one or two days as examples, such as one weekday and one weekend day. Note that in both of these methods the diet history is taken using an “open-ended” question. Patients are not asked what they ate for breakfast, lunch, and dinner. Anchoring food intake to predefined meals may bias the patient to provide an inaccurate history.
The third method is food frequency.