This patient had hives and angioedema. This is an extensive case with very large plaques with deep swelling. The major complaint was discomfort and some itching.

The plaques of angioedema are uniform, tense, non-pitting, and non-erythematous. The borders may be well defined. These plaques lack the faint white or red halo found with hives.

Swelling of the lips is a classic sign of angioedema. Swelling may be massive and the only manifestation of the disease.