CHAPTER 67 Peripheral Nerve Blocks
3 What are the risks of performing a peripheral nerve block?
There may be inadvertent damage to anatomic structures by the advancing needle. Examples include direct trauma to the nerve or spinal cord by intraneural injection of local anesthetic, nerve laceration, vascular injury with resulting hematoma formation, or pneumothorax.
The drugs that are injected may have undesirable local and systemic effects. Allergic reactions to local anesthetics are rare. Ester local anesthetics are derivatives of para-aminobenzoic acid, a known allergen, and therefore more likely to cause allergic reactions than the amide local anesthetics. Any local anesthetic injected intravascularly has the potential for systemic reactions, including seizures and cardiovascular collapse.