60: Chronic Occlusion of a Superficial Femoral Artery

Published on 02/03/2015 by admin

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Last modified 22/04/2025

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CASE 60 Chronic Occlusion of a Superficial Femoral Artery

Angiography

Arterial access was obtained in the left common femoral artery and a 4 French Omniflush catheter was used to perform angiography. Aortography confirmed wide patency of the common iliac stents (Figure 60-2). Selective right femoral angiography and runoff was performed by passing a hydrophilic glide wire over the bifurcation using the Omniflush catheter and then exchanging for a 4 French RIM catheter. Angiography found a mild stenosis in the common femoral artery, followed by a diffusely diseased segment of the proximal SFA of moderate stenosis and then a long segment of total occlusion (Figure 60-3). There was reconstitution of the distal SFA above the adductor canal via collaterals from the profunda femoris (Figures 60-4 through 60-6). Below the knee, the anterior tibial was occluded; however,two-vessel runoff was present to the foot via the posterior tibial and peroneal arteries. Based on the patient’s profound symptoms, her anatomy, and her comorbid conditions, it was decided to proceed with an intervention to the right SFA.

An Amplatz wire was placed through the RIM catheter in the right external iliac. Attempts were made to get a 6 French long Ansel sheath to pass over the bifurcation from the left femoral artery over the Amplatz wire; however, the sheath would not advance past the previously placed iliac stents. A longer dilator and a 0.018 inch system were tried without success. In order to avoid damage to the prior iliac stents, the operator decided to access the right femoral artery in an antegrade fashion. Access to the right common femoral artery was obtained with a micropuncture kit and a 6 French Ansel sheath was inserted. Following the administration of unfractionated heparin, the occluded segment of the right SFA was probed with a glide wire backloaded on a hydrophilic catheter (VERT catheter). With gentle manipulations, the catheter and wire successfully crossed the SFA occlusion and the distal tip of the guidewire appeared to move freely within the popliteal artery. The glide wire was removed; contrast injected through the catheter confirmed intraluminal placement (Figure 60-7). Systemic heparin was administered to achieve a therapeutic activated clotting time of more than 250 seconds. A 0.018 inch interventional guidewire was inserted and the hydrophilic catheter exchanged for a balloon catheter. The entire SFA was then dilated with a 4 mm diameter by 80 mm long balloon (Figure 60-8). Substantial residual stenosis and recoil remained after balloon dilatation, and thus the operator decided to place multiple stents. Beginning in the distal SFA, a 6 mm diameter by 150 mm long, self-expanding nitinol stent was deployed, followed by a 6 mm diameter by 120 mm long self-expanding nitinol stent. A 1 to 2 cm gap was initially left at the ostium of the SFA. The stented segment and ostial SFA were further dilated with the 4 mm by 80 mm balloon to high atmospheres (Figure 60-9). Subsequent angiography confirmed an excellent result in the stented segment (Figure 60-10); however, the ostium of the SFA had greater than 30% residual stenosis and an ulcerated dissection (Figure 60-11). The operator placed another stent (6 mm diameter by 20 mm long self-expanding nitinol), taking great care to avoid impingement on the profunda femoris and postdilated with a 4 mm diameter by 80 mm long balloon (Figure 60-12). The final angiogram demonstrated sealing of the dissection with no residual stenosis, no impingement on the profunda femoris, and no signs of distal embolization (Figure 60-13).

Discussion

Disease of the SFA is found in 80% to 90% of patients with claudication.1 Guidelines were created to help manage patients with peripheral arterial disease involving the femoral-popliteal arteries.2 The TASC criteria classifies femoropopliteal lesions from A to D, with TASC A and B lesions typically being treated percutaneously and TASC D lesions being treated surgically, due to the poor long-term patency of endovascular therapy for this subset. Surgery is preferred for TASC C lesions unless the patient has substantial comorbid conditions resulting in excessive surgical risk. The lesions in the case presented here would be classified TASC C or D and the long term patency would likely have been greater with surgical rather than endovascular revascularization. However, the decision regarding the method of revascularization is complex and must consider other medical conditions, patient preference, and technical feasibility. For example, in this case, the presence of multiple comorbid conditions including advanced age, diabetes, and both prior myocardial infarction and stroke increased her risk of surgery. Endovascular therapy was thought to be lower-risk and appeared technically feasible. Importantly, this mode of revascularization would be unlikely to interfere with surgical options if needed at a later date, leading to the decision to pursue endovascular therapy.

With the recent advances in technique and device technology, many chronic SFA occlusions are currently approachable with a high rate of success, offering hope to patients who may have not had other options. One such method is the SAFARI technique (subintimal arterial flossing with antegrade-retrograde intervention) where the operator approaches the occlusion from both above and below with a second access site in the pedal vessels or popliteal artery. The traditional technique approaches the occlusion from above with a guidewire and catheter. Using this technique, the operator may pass the wire and catheter into a dissection plane just distal to the exit site of the occlusion and find it difficult to reenter the true lumen. Several devices have been created to facilitate reentry into the true lumen (the Outback and Pioneer catheters). Armed with these devices, the interventionalist may attempt to cross a chronically occluded SFA using the traditional wire technique and, if the wire fails to reenter the true lumen distally, then employ one of these devices to redirect the wire into the true lumen. With this approach, procedural success rates greater than 80% to 90% are common.

Once a wire has been positioned distally, a variety of techniques have been proposed to treat the occluded segment. These include balloon angioplasty, directional or orbital atherectomy, self-expanding stents, and covered self-expanding stents. There are little data available comparing these techniques and most information is generated from registries and self-reported case series. With this in mind, at the present time, there does not appear to be a clearly superior mode of therapy for the treatment of a chronically occluded SFA. The relatively high rate of restenosis, on the order of 20% to 50%, remains a major limitation for all of these devices.3 There are also limited data available addressing the issue of restenosis. Nevertheless, with current endovascular techniques, aggressive medical therapy, and close follow-up, the majority of these patients have an improvement in their quality of life.