41

Published on 10/05/2015 by admin

Filed under Gastroenterology and Hepatology

Last modified 22/04/2025

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CASE 41

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History: An 80-year-old woman presents with left-sided abdominal pain and vomiting.

1. What is your differential for the location and diagnosis of the large calcification seen in the right upper quadrant of the abdomen in figure A? (Choose all that apply.)

A. Adrenal gland; e.g., tuberculosis

B. Gallbladder; e.g., porcelain gallbladder

C. Liver; e.g., hydatid cyst

D. Kidney; e.g., calcified cyst

E. Abdominal wall; e.g., old hematoma

2. Based on the figures, which of the following is the most likely diagnosis?

A. Adrenal gland tuberculosis

B. Porcelain gallbladder

C. Hydatid cyst of the liver

D. Calcified renal cyst

E. Abdominal wall, old hematoma

3. What is the usual etiologic basis for this condition?

A. Granulomatous reaction

B. Systemic hypercalcemia

C. Cystic duct obstruction

D. Old hemorrhage

4. Name the major complication associated with this finding.

A. Gallbladder abscess

B. Gallbladder perforation

C. Gallbladder carcinoma

D. Emphysematous cholecystitis

ANSWERS

CASE 41

Porcelain Gallbladder

1. B, C, D, and E

2. B

3. C

4. C

References

Kane RA, Jacobs R, Katz J, Costello P. Porcelain gallbladder: ultrasound and CT appearance. Radiology. 1984;152:137–141.

Stephen AE, Berger DL. Carcinoma in the porcelain gallbladder: a relationship revisited. Surgery. 2001;129:699–703.

Cross-Reference

Gastrointestinal Imaging: THE REQUISITES, 3rd ed, p 254.

Comment

It is thought that chronic cystic duct obstruction and subacute inflammation are the basis of gallbladder wall calcification. Quite often the calcified gallbladder is small and contracted (unlike the example in this case), and it is easy to confuse the finding with calcified gallstones (see figures). However, the porcelain gallbladder carries its own inherent risk, which much outweighs gallstones. The risk of developing carcinoma of the gallbladder in an untreated porcelain gallbladder is high, somewhere between 10% and 30%. Plain film and ultrasound can confuse calcified gallstones and a porcelain gallbladder. However, multidetector CT is much more adept at distinguishing the differences (see figures) and can show the cystic duct obstruction as well.