10: MUSCULOSKELETAL

Published on 16/06/2015 by admin

Filed under Basic Science

Last modified 16/06/2015

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Etodolac (Lodine)

CLASSIFICATION

Nonsteroidal antiinflammatory analgesic

ACTIONS

Inhibits prostaglandin synthesis and produces analgesic and antiinflammatory effects. These actions will reduce the intensity of the pain stimulus reaching sensory nerve endings.

USES

• Acute long-term treatment of pain associated with osteoarthritis and rheumatoid arthritis

CONTRAINDICATIONS AND PRECAUTIONS

• Active peptic ulcer, gastrointestinal (GI) ulceration, chronic inflammation of GI tract, GI bleeding disorders

• History of allergy or hypersensitivity to aspirin or other nonsteroidal antiinflammatory drugs (NSAIDs)

• Impaired renal and hepatic function

SIDE EFFECTS

**Indigestion,** dizziness, headache, abdominal pain or cramps, diarrhea, nausea

• Causes less GI irritation and bleeding tendencies than other NSAIDs

NURSING IMPLICATIONS

1. Assess joints for pain and signs of inflammation.

2. Inspect affected joints for level of mobility.

3. *Monitor complete blood count and liver and renal function.*

4. *Observe for bleeding or bruising.*

5. Teach the patient to swallow the capsules whole and not to crush or chew.

6. Teach the patient not to take aspirin or alcohol during therapy.