Pharmacogenomics

Published on 16/06/2015 by admin

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Last modified 16/06/2015

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CHAPTER 29 Pharmacogenomics

I. Introduction

B. There are small variations in genetic sequencing among humans. Genetic polymorphisms are DNA sequencing variations that occur with at least a frequency of 1% in the population; polymorphisms are responsible for significant alterations in the way a given person responds to a given drug. The effects may be pharmacokinetic or pharmacodynamic in nature; examples are given in the following review.