CHAPTER 13 Gastrointestinal Disorders
|H. pylori||Nonsteroidal anti-inflammatory drugs (NSAIDs)|
|Direct mucosal damage caused by hypergastrinemia||Direct mucosal damage associated with prostaslandin inhibition|
|Ulcers are superficial; chronically inflamed||Ulcers are deep; no inflammation|
|Symptoms: epigastric pain (may be nocturnal), nausea, indigestion, fatigue||Patients are usually asymptomatic; complications cause bleeding perforation|
Box 13-1 Treatment Regimens for H. Pylori
Gastroesophageal reflux disease (GERD), also called acid reflux disease, occurs when liquid from the stomach regurgitates into the esophagus. This liquid may contain stomach acids and bile. In some cases, the regurgitated stomach liquid can cause inflammation (esophagitis), irritation, and damage to the esophagus.