Chapter 133 Late Effects of HSCT
Many children who receive hematopoietic stem cell transplantation (HSCT) become long-term survivors. Besides chronic graft versus host disease (GVHD), long-term complications include impaired growth, neuroendocrine dysfunction, delayed puberty, infertility, second malignancies, cataracts and other ocular complications, leukoencephalopathy, and cardiac and pulmonary dysfunction (see Table 133-1 on the Nelson Textbook of Pediatrics website at
www.expertconsult.com).
DLCO, carbon monoxide diffusing capacity; FEV, forced expiratory volume; FVC, forced vital capacity; GVHD, graft versus host disease; TLC, total lung capacity.
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