Duodenal Metastases and Lymphoma

Published on 19/07/2015 by admin

Filed under Radiology

Last modified 19/07/2015

Print this page

rate 1 star rate 2 star rate 3 star rate 4 star rate 5 star
Your rating: none, Average: 0 (0 votes)

This article have been viewed 1300 times

 Metastases: Bull’s-eye or “target” lesion; submucosal or polypoid mass

image Lymphoma: Bulky submucosal mass without obstruction
• Best imaging tool: Upper GI series, CECT
• Metastases: “Target” or bull’s-eye lesion with rounded submucosal mass

image Luminal obstruction and ulceration are common
• Lymphoma: Large smooth or lobulated submucosal mass 

image Aneurysmal dilation of lumen without obstruction
• Direct invasion: From primary cancer of pancreas, colon, kidney, gallbladder

image 

TOP DIFFERENTIAL DIAGNOSES

• Villous adenoma, duodenal carcinoma, secondary duodenal invasion, duodenal GIST
• 
• 
• 

PATHOLOGY

• Etiology

image Metastases: Melanoma, cancer of breast, lung, colon, pancreas, or kidney
image Lymphoma: Non-Hodgkin lymphoma of B-cell origin or mucosa-associated lymphoid tissue

CLINICAL ISSUES

• Most common signs/symptoms: Abdominal pain, nausea, vomiting, weight loss, palpable mass, upper GI bleeding

image 

DIAGNOSTIC CHECKLIST

• Consider duodenal carcinoma (usually obstructs lumen)
• Lymphoma: Bulky submucosal mass without obstruction
image
(Left) Spot film from from an upper GI series shows an ulcerated mass image arising from the 2nd portion of the duodenum. There is a persistent pooling of barium within the lesion after the remainder of the duodenum has cleared.

image
(Right) Axial CECT in the same patient reveals a high-attenuation mass image within the wall of the 2nd duodenum. A metastatic tumor was confirmed at surgery with the same histology as the primary colon cancer.
image
(Left) Small bowel follow-through in a liver transplant recipient, who presented with upper gastrointestinal pain and bleeding, shows a large amorphous collection of barium image apparently arising from, and in continuity with, the distal duodenum. There is no evidence of bowel obstruction.

image
(Right) Axial CECT in the same patient shows a large soft tissue density mass image arising from the distal duodenum. This is a good example of aneurysmal dilation of the bowel lumen caused by lymphoma.

TERMINOLOGY

Definitions

• Involvement of duodenum with malignant lymphoma or metastatic disease

IMAGING

General Features

• Best diagnostic clue

image Metastases: Bull’s-eye or “target” lesion; submucosal or polypoid mass
image Lymphoma: Bulky submucosal mass without obstruction of lumen
• Location

image Submucosal lesion in any portion of duodenum
• Size

image 1-5 cm
• Morphology

image Lymphoma: Smooth submucosal, often bulky mass

Fluoroscopic Findings

• Upper GI

image Metastases: “Target” or bull’s-eye lesion with rounded submucosal mass; luminal obstruction and ulceration are common

– 

Buy Membership for Radiology Category to continue reading. Learn more here